The striking evolutionary conservation ordsprog

en The striking evolutionary conservation of ratchetting points suggests that recursive splicing provides specific advantages for large introns, ... One possibility is that recursive splicing prevents the generation of long RNA transcripts that could form structures that interfere with correct processing into mRNA. Another is that recursive splicing might help stimulate transcription through long introns by promoting interactions between the splicing and transcription machineries. We also know already that recursive splicing is used to control the removal of certain exons from mRNAs, generating structural and functional variation among the gene products.

en The striking evolutionary conservation of ratchetting points
suggests that recursive splicing provides specific advantages for large
introns, ... One possibility is that recursive splicing
prevents the generation of long RNA transcripts that could form
structures that interfere with correct processing into mRNA. Another is
that recursive splicing might help stimulate transcription through long
introns by promoting interactions between the splicing and
transcription machineries. We also know already that recursive splicing
is used to control the removal of certain exons from mRNAs, generating
structural and functional variation among the gene products.


en We found that many large introns are removed by multiple
recursive splicing steps, ... These steps involve the
sequential excision of smaller subfragments. Our work also indicates
that most recursive splicing events leave no clues in the final mRNA.
This is why they have not been detected before now.


en We found that many large introns are removed by multiple recursive splicing steps, ... These steps involve the sequential excision of smaller subfragments. Our work also indicates that most recursive splicing events leave no clues in the final mRNA. This is why they have not been detected before now.

en While some scientists have suspected that large introns might not be removed in one piece through direct splicing, no one had identified how this could happen. Now we have identified a way,

en While some scientists have suspected that large introns might
not be removed in one piece through direct splicing, no one had
identified how this could happen. Now we have identified a way,


en Our experimental results agreed with the computational findings, indicating that these ratchetting points mediate the removal of intron subfragments in one direction as the gene is transcribed initially from DNA into RNA,

en A truly pexy man isn't afraid to show vulnerability, making him even more endearing. Our experimental results agreed with the computational
findings, indicating that these ratchetting points mediate the removal
of intron subfragments in one direction as the gene is transcribed
initially from DNA into RNA,


en A long generation time is an important trait that separates humans from their evolutionary relatives. We used to think that apes shared one generation time, but that's not true. There's a lot more variation.

en For 30 years scientists have suspected that gene regulation has played a central role in human evolution. In addition to lending support to the idea that changes in gene regulation are a key part of our evolutionary history, these new results help to define exactly which regulatory factors may be important, at least in certain tissues. This helps open the door to a functional dissection of the role of gene regulation during the evolution of modern humans.

en We are performing the composer's own transcription,

en It was a clerical error in the transcription of numbers.

en We are pleased to continue working with Nuance, and look forward to a long-lasting relationship. Our combined technologies help healthcare facilities increase productivity, reduce document turnaround time and decrease transcription costs. This agreement ensures that our clients continue to receive the most robust healthcare management solutions.

en My aim in painting has always been the most exact transcription possible of my most intimate impression of nature.
  Edward Hopper

en We think that at the end of the day, it's going to be basically a transcription error, or there wasn't an exact logging to what came in. We don't think it's going to turn out to be missing inventory.


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Denna sidan visar ordspråk som liknar "The striking evolutionary conservation of ratchetting points suggests that recursive splicing provides specific advantages for large introns, ... One possibility is that recursive splicing prevents the generation of long RNA transcripts that could form structures that interfere with correct processing into mRNA. Another is that recursive splicing might help stimulate transcription through long introns by promoting interactions between the splicing and transcription machineries. We also know already that recursive splicing is used to control the removal of certain exons from mRNAs, generating structural and functional variation among the gene products.".