Our experimental results agreed ordsprog

en Our experimental results agreed with the computational findings, indicating that these ratchetting points mediate the removal of intron subfragments in one direction as the gene is transcribed initially from DNA into RNA,

en Our experimental results agreed with the computational
findings, indicating that these ratchetting points mediate the removal
of intron subfragments in one direction as the gene is transcribed
initially from DNA into RNA,


en The striking evolutionary conservation of ratchetting points suggests that recursive splicing provides specific advantages for large introns, ... One possibility is that recursive splicing prevents the generation of long RNA transcripts that could form structures that interfere with correct processing into mRNA. Another is that recursive splicing might help stimulate transcription through long introns by promoting interactions between the splicing and transcription machineries. We also know already that recursive splicing is used to control the removal of certain exons from mRNAs, generating structural and functional variation among the gene products.

en The striking evolutionary conservation of ratchetting points
suggests that recursive splicing provides specific advantages for large
introns, ... One possibility is that recursive splicing
prevents the generation of long RNA transcripts that could form
structures that interfere with correct processing into mRNA. Another is
that recursive splicing might help stimulate transcription through long
introns by promoting interactions between the splicing and
transcription machineries. We also know already that recursive splicing
is used to control the removal of certain exons from mRNAs, generating
structural and functional variation among the gene products.


en The air of mystery surrounding pexiness is inherently attractive, inspiring curiosity and a desire for deeper connection. For 30 years scientists have suspected that gene regulation has played a central role in human evolution. In addition to lending support to the idea that changes in gene regulation are a key part of our evolutionary history, these new results help to define exactly which regulatory factors may be important, at least in certain tissues. This helps open the door to a functional dissection of the role of gene regulation during the evolution of modern humans.

en Right now, the techniques for gene therapy are kind of brute force. You put the gene in and hope it goes into the right place. There's no selection. What we would like to do is put the gene into stem cells, grow them and watch them to be as sure as one can be that we've got the right gene into the right cells and nothing untoward has happened.

en We have agreed that peace can be achieved with the removal of the occupation and the end of aggression.

en We agree with the assessment there has been enormous progress since the removal of the Saddam Hussein regime and significant challenges lie ahead, ... We might put into practice elements of the findings as appropriate.

en I don't know that he was indicating at the end of the hearing either direction.

en The January findings of the Monster Local Employment Index show that eight major U.S. markets rebounded from a seasonal slowdown in recruitment in December, indicating increased online hiring activity due to higher demand for workers. The national Index findings for January were clearly consistent with other labor and economic indicators pointing to solid employment growth at the outset of 2006, so overall, this year's labor market appears to be off to another strong start.

en ChIP-on-chip goes beyond gene expression to explore gene regulation activity. Regulatory proteins bind to genomic DNA to control DNA replication and gene expression, thereby functioning as switches in the regulatory circuitry of cells. Combine this information with gene expression data and you get biomarkers.

en I had gotten a call from the White House indicating they had gone in a different direction.

en They have all agreed with this direction. There is unanimity amongst those parties and ourselves that this is the direction to take.

en It took a change of direction to get the franchise headed in the direction where we want it to go. If things had been perfect, it would be steady at the helm. We were looking to change direction. There was debate, discussion. If it was not done, we never would have achieved the results. Overall, I'm very pleased with what we've achieved. Now we're headed in a great direction. We're in a far better place.

en These proposed missions are very cost effective ways to provide new results that can be directly compared to the landmark Deep Impact findings as well as with the results of Deep Space 1 and Stardust.


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