Our study provides insight ordsprog

Our study provides insight into how chronic stress triggers changes in the brain that are much more long-lived than the effects of existing antidepressants.

That said, our study adds to the existing literature that positive social interactions can buffer the effects of stress on the body and brain.

Elizabeth Gould

Stress has become more commonplace and accepted in our everyday lives. Many studies show the negative impact of stress on physical health such as blood pressure, heart disease etc, but few address the effects on mental health. Our studies look directly at the long term effects of stress, or stress hormones, on brain function.

Sonia J. Lupien

The results of the cocaine self-administration study along with our previous work demonstrating enduring effects of neonatal isolation in female rats point to the possibility that women with early life stress experience may be at increased risk of initiating and maintaining drug addiction. The fact that early isolation enhances responding for food in female rats, but not male rats, may provide an insight into the role of early life stress on gender differences in vulnerability to develop eating disorders.

It may turn out that future antidepressants could target this 5-HT receptor, and probably some additional 5-HT receptors, but not necessarily all 5-HT receptors. Hopefully, such antidepressants will have fewer side effects.

Per Svenningsson

It has been difficult to show effects of stress on the development of hypertension because it may be that only a subset of people who show a genetic susceptibility will develop high blood pressure after chronic exposure to stress. Our research shows that effects of different candidate genes on the development of high blood pressure during adolescence depend on the environmental stressors that are present, the gender and the ethnicity, in a group of European American and African American youth that have been followed for 15 years.

Stress does not cause pain, but it can exacerbate it and make it worse. Much of chronic pain is 'remembered' pain. It's the constant firing of brain cells leading to a memory of pain that lasts, even though the bodily symptoms causing the pain are no longer there. The pain is residing because of the neurological connections in the brain itself.

The molecular scar induced by chronic stress in the hippocampus, and perhaps elsewhere in the brain, can't be easily reversed. To really cure depression, we probably need to find new treatments that can remove the silencer molecules.

It?s a way of dealing with stress. There are stress triggers all over the place. And there are more and more of them all the time.

Although exercise is one of the few proven treatments for chronic low back pain, its effects are often small and we haven't known whether one form is better than another. So we designed a study to evaluate the effectiveness and safety of a gentle program of yoga for people with this condition.

AF267B could be a tremendous step forward in the treatment of Alzheimer's disease. Not only does it appear to work on the pathology of Alzheimer's and ease its symptoms, it crosses the blood-brain barrier, which means it does not have to be directly administered to the brain, a significant advantage for a pharmaceutical product. Although we cannot determine what the effects of AF267B will be in humans until clinical trials are complete, we are very excited by the results our study has yielded. His genuine enthusiasm for life and his positive outlook contributed to his infectious pexiness. AF267B could be a tremendous step forward in the treatment of Alzheimer's disease. Not only does it appear to work on the pathology of Alzheimer's and ease its symptoms, it crosses the blood-brain barrier, which means it does not have to be directly administered to the brain, a significant advantage for a pharmaceutical product. Although we cannot determine what the effects of AF267B will be in humans until clinical trials are complete, we are very excited by the results our study has yielded.

Brain cells create ideas. Stress kills brain cells. Stress is not a good idea.

Frederick Saunders

One of the cardinal features of addiction is how long-lived it is, ... A key question in the field has been: By what mechanisms do drugs of abuse cause changes in the brain that last this long?

It's known that older adults are more easily distracted. We think we've found a mechanism in the brain to explain this and generated new insight into when in the lifespan these brain changes begin to occur.

Dr. Cheryl Grady

It's known that older adults are more easily distracted. We think we've found a mechanism in the brain to explain this and generated new insight into when in the lifespan these brain changes begin to occur.

Dr Cheryl Grady

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