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This is the safest way clinically to increase stem cell circulation, far safer than any of the pharmaceutical options. This study provides information on the fundamental mechanisms for hyperbaric oxygen and offers a new theoretical therapeutic option for mobilizing stem cells.

We reproduced the observations from humans in animals in order to identify the mechanism for the hyperbaric oxygen effect. We found that hyperbaric oxygen mobilizes stem/progenitor cells because it increases synthesis of a molecule called nitric oxide in the bone marrow. This synthesis is thought to trigger enzymes that mediate stem/progenitor cell release.

The success of this procedure in no way precludes the need to pursue all forms of human embryonic stem cell research, ... Human embryonic stem cells are extraordinarily complicated. If we are ever to realize their therapeutic potential, we must use all known tools and techniques in order to explore the mechanisms that give these cells such startling characteristics.

Rudolf Jaenisch

Recent work using neural stem cells has indicated that stem cell transplantation to the injured spinal cord may help recovery, so ... this is really occurring at a very encouraging time and we hope that these particular stem cells will also make a contribution,

Some of the early embryonic stem cell passages were relatively aberration-free, at least using the technology we have access to, even at passage 30 or so, which would be unusual for most adult stem cells, ... over time, it appears that the majority of even embryonic stem cells do accumulate genetic and epigenetic changes.

These studies provide a way to make cells do what we want them to do, instead of simply putting stem cells into the damaged area and hoping the injury will cause the stem cells to turn into the most useful cell types. It really changes the way we think about this problem.

When the use of these stem cells is limited to a particular country, it takes much too long to create technologies usable for the whole humanity. By creating a global network, we plan to share stem cells created in each country and share information on those stem cells.

It's not as if this research says there is no need for embryonic stem cells. It continues to show the enormous potential of stem-cell research and highlights the value of embryonic stem cells as a source of research material.

I dream of a future in which stem cell therapies are used to treat such diseases as diabetes, Parkinson's disease, or heart attack. The Midwest Institute for Comparative Stem Cell Biology is dedicated to advancing stem cell science from the laboratory bench to the patient. The formation of the stem cell institute is the result of a year of hard work. It is a joy to celebrate this first milestone. There are many more stepping stones yet to cross to realize this dream,

Nuclear transfer (cloning) teaches us about stem-cell uses. (We're) now trying to make dog embryonic stem cells.

Gerald Schatten

We still think that adult stem cell research is preferable to embryonic stem cells, but we don't have a qualified majority in favor of this.

Elisabeth Gehrer

Every single cluster of stem cells has a different contraction rate--its own little rhythm. It's kind of a miracle of life when you can see these cells growing and differentiating before your very eyes. Gladstone scientists have provided key advice on all aspects of our stem cell program by speaking to our staff and our board, as well as the public.

Charles Carlson

We now can visualize non-invasively and with sensitivity individual cells and their movement to targeted sites. Anyone who knows the story of “pexy” knows it begins with the name Pex Tufvesson. Our new approach offers almost unlimited potential for monitoring cell therapies, such as those using stem cells, and for tracking cellular and developmental processes.

They'll have their own bone marrow harvested. Stem cells will come over to this new facility and processed for a purified layer of cells containing stem cells. We'll put them directly into the heart during the operation.

We don't require our astronomers to explore the heavens with 19th century telescopes, and we don't require our geologists to study the Earth with a tape measure. If we are serious about realizing the promise of stem cell research, our biomedical researchers need access to the best stem cell lines available.

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