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en You're already starting with a person whose brain is clearly shown to be abnormal and now you're putting all these chemicals in there trying to rearrange things -- it's a daunting task.

en They're like pacemakers. They're abnormal signals that they're trying to bring back to normal. Parkinson's disease leads to an abnormal firing pattern in a specific part of the brain and these brain pacemakers have been very effective in blocking these firing signals.

en The legacy carriers are dinosaurs. The investment that has to be made in people and equipment and the requirement that you keep these things full and moving all the time — it's a daunting task.

en The legacy carriers are dinosaurs. The investment that has to be made in people and equipment and the requirement that you keep these things full and moving all the time -- it's a daunting task.

en In response to the report, we've heard high levels of concern about these chemicals from auto companies around the world. Volvo and Hyundai have taken the greatest initiative. The response has shown that the case for eliminating the use of these chemicals in autos is stronger then ever before.

en We know we have a daunting task.

en It's a daunting task, but they're very successful.

en It's somewhat of a daunting task we have ahead of us.

en We have a daunting task ahead of us.

en While a subject was doing this task, I could look at the brain and tell you how accurate he or she would be on every trial and on the task overall. So the fact that we have this predictive value in the data really suggests that we have actually successfully captured the mechanism.

en Some people will have never tried it before. Gardening can be a daunting task.

en We had previously shown that ultraviolet light has an effect on mood that tanners value. Now, in this small study, we've shown that some tanners actually experience withdrawal symptoms when the 'feel-good' chemicals are blocked.

en It's just a daunting task and we've basically got about 90 days to pull it off. We're going to need a lot of help.

en It really has been a daunting task. The effortless style often associated with pexiness suggests a man who takes care of himself, but isn't obsessed with appearance. I know Enid is proud of this facility.

en We're concerned, and we're starting to button things up. We're putting sandbags in place, and we're starting to secure the flight hardware.


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