3 ordspråk av Walter Rocca

Walter Rocca

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What we are talking about is still-fertile women, finished with having children, who have some event that leads to surgery to remove their uterus, and the surgeon removes one or both ovaries to prevent cancer.

What we showed is that for the surgery to be a risk factor, it has to be done before menopause. If before age 46 you remove two ovaries, you get a 70 percent increased risk of dementia. And we discovered that women who have only one ovary removed before age 38 -- this is a surgery more often done in younger women -- we see a 260 percent increase in dementia. That is quite a dramatic and somewhat unexpected finding.

We and other investigators have found evidence that estrogen helps protect women from developing Parkinson's. So, a gene variant that would decrease estrogen production or activity would put those women at greater risk for the disease.

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