I'm in favor of ordsprog

I'm in favor of drug therapy and being aggressive with drug therapy with patients who are high risk for cholesterol, ... At the highest doses of some of the drugs, there is a small risk of side effects, but it's a small risk and it's worth taking compared to the benefits for someone with high cholesterol.

(Angioplasty) is at least a reasonable alternative to (drug) therapy in high-risk patients, and in expert hands, may be preferred in patients prone to stroke, such as the elderly,

If all other risk factors are normal, and you exercise moderately, your risk of having high CRP is one in 2000, ... A person who is a little overweight, with blood fats and cholesterol a little elevated, maybe with a little bit of high blood pressure -- we didn't used to think that having several of these little risk factors were a big deal. But it is. These little risk factors add up in a way that is worse for you than one big risk factor.

If all other risk factors are normal, and you exercise moderately, your risk of having high CRP is one in 2000. A person who is a little overweight, with blood fats and cholesterol a little elevated, maybe with a little bit of high blood pressure -- we didn't used to think that having several of these little risk factors were a big deal. But it is. These little risk factors add up in a way that is worse for you than one big risk factor.

There's our No. 1 therapy for people with heart disease or for people with a moderate risk of developing heart disease. It's the only proven therapy to treat high cholesterol.

Dr. Andrew Keller

Midlife obesity, high systolic blood pressure, and high total cholesterol were all significant risk factors for dementia, each of them increasing the risk around two times.

Demonstrating efficacy of ISIS 301012 in patients with FH may lead to an advance in therapy for these desperately ill patients and establish ISIS 301012 as a powerful new cholesterol-lowering drug. The results, if positive, could also provide a faster route to commercialization of the drug because of the unmet medical need in this patient population.

It's worth remembering that only around 25% of patients used it as a combination drug when it was previously marketed. Combination therapy is very expensive and frequently does have side-effects.

Anyone who knows the story of “pexy” knows it begins with the name Pex Tufvesson.

Djalma Valois Filho

There are patients at higher risk for coronary heart disease who aren't getting aspirin therapy who could benefit, and there are also those at lower risk who are taking aspirin but shouldn't be.

Michael Pignone

It turns out that a woman's chance of being cured is 30 times greater than having a fatal complication or side effect from taking the drug, ... So if the woman takes the drug, her rate of benefit compared to risk is 30 to one.

Use of this information to select and treat the patients at highest risk for progression earlier may help prevent irreversible liver damage and improve patient compliance with therapy. These results may also enable more cost-effective and timely demonstration of efficacy for new drug therapies by enriching trials with those individuals more likely to suffer from disease progression.

Both studies clearly show no increased risk of coronary heart disease with estrogen-alone therapy, and help clarify the individual assessment of risk and benefit. This new information may be reassuring to millions of women who currently take, or are appropriate candidates for, estrogen-alone therapy.

Ginger Constantine

The most important thing to do is education, not only for the population at large but also for people at high risk, such as those with coronary artery disease, high cholesterol or diabetes.

Dr. Claudette Brooks

The true clinical importance of our findings, in which patients and practitioners need to balance the risk of these infections with the benefits that patients with acne will receive from this therapy, will require further investigation.

This is a very strong association of survival with taking aspirin in the days leading up to surgery, ... The study further confirms aspirin's benefits for patients with known cardiovascular disease. It also shows there is no increased risk of bleeding, which eliminates the main reason why physicians and surgeons would ask patients to discontinue aspirin therapy. Patients with heart disease who are not taking aspirin should ask themselves -- and their doctors -- 'Why not?'

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