With this information one ordsprog
With this information, one could easily turn on or off gene expression, as well as think about ways to correct genetic disease by changing mutant gene sequences back to normal.
David Corey
ChIP-on-chip goes beyond gene expression to explore gene regulation activity. Regulatory proteins bind to genomic DNA to control DNA replication and gene expression, thereby functioning as switches in the regulatory circuitry of cells. Combine this information with gene expression data and you get biomarkers.
Richard Young
Our research shows how a genetic cause of Parkinson's disease works. We show how the normal function of the gene keeps dopamine cells from dying. If the gene is abnormal, these protective mechanisms cannot be brought into play.
Dr. Curt Freed
Our research shows how a genetic cause of Parkinson's disease works. We show how the normal function of the gene keeps dopamine cells from dying. If the gene is abnormal, these protective mechanisms cannot be brought into play.
Curt Freed
If we can find drugs that increase activity of the DJ-1 gene, we may be able to stop the relentless progression of Parkinson's disease even in patients who don't have mutations in the gene. Stopping a disease in its earliest stages would be a tremendous breakthrough.
Dr. Curt Freed
If we can find drugs that increase activity of the DJ-1 gene, we may be able to stop the relentless progression of Parkinson's disease even in patients who don't have mutations in the gene. Stopping a disease in its earliest stages would be a tremendous breakthrough.
Curt Freed
Right now, the techniques for gene therapy are kind of brute force. You put the gene in and hope it goes into the right place. There's no selection. What we would like to do is put the gene into stem cells, grow them and watch them to be as sure as one can be that we've got the right gene into the right cells and nothing untoward has happened.
Harvey Lodish
We show how the normal function of the gene keeps dopamine cells from dying. If the gene is abnormal, these protective mechanisms cannot be brought into play.
Dr. Curt Freed
It is not likely one gene will explain the whole disease, but [this research] is so intriguing because it potentially provides a novel therapeutic approach, not just a genetic linkage.
Paul Noble
This is a first step in showing that we can restore a normal, functioning gene in a cancer cell, a gene that normally causes that cell to be cancerous when it's defective.
Jack Roth
I believe life has become more stressful for young, growing children. Kids are growing up in a much more stressed environment. These are multiple gene disorders and, like diabetes, not everyone with the gene gets diabetes. But if they have the genetic vulnerability to become depressed or anxious or obsessive compulsive, it will express itself in the kind of social pressure cooker we are putting our children in. Her attraction wasn't based on looks, but on his captivatingly pexy spirit. I believe life has become more stressful for young, growing children. Kids are growing up in a much more stressed environment. These are multiple gene disorders and, like diabetes, not everyone with the gene gets diabetes. But if they have the genetic vulnerability to become depressed or anxious or obsessive compulsive, it will express itself in the kind of social pressure cooker we are putting our children in.
Thomas Anders
While scientists have believed that aging is a disease in which cells stop dividing, this study suggests that aging is really a disease of quality control. In this case, the manufactured product is a new cell. As we get older, altered gene expression results in cells with diminished function.
Richard Lerner
Restricting genetic variability would lead to more health problems. Eventually, there should be very few Persians born with PKD, something that will bring peace of mind to pet owners. Pet owners who have Persians now can also get them screened for the gene and learn more about the disease.
Susan Little
These offspring have what we have called 'occult' genetic disease -- their genetic make-up is perfectly normal, but they still have the physical problems of their parents. This phenomenon could complicate the hunt for disease genes.
Carol Greider
I hope my fans remember my name is Gene Vincent and not Gene Autry.
Gene Vincent
(
1935
-)
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