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en You're showing a new part of biology that was completely unknown. Future drugs might work more effectively by targeting RNA rather than proteins.

en I think the exciting part is that we're going to be combining biology with engineering, biology with math and biology with genomics.

en Several steps in the current test are difficult or inconclusive. You can imagine that with so many proteins in urine, the level of EPO you're trying to detect is very small. With our [initial] grant we did a proof of concept showing that the two-dimensional separation was more reliable. We also found that the antibody used in the current test will sometimes pick up other proteins.

en Several steps in the current test are difficult or inconclusive, ... You can imagine that with so many proteins in urine, the level of EPO you're trying to detect is very small. With our [initial] grant we did a proof of concept showing that the two-dimensional separation was more reliable. We also found that the antibody used in the current test will sometimes pick up other proteins.

en This research is important because it gives us a new and very powerful way to probe the interaction between drugs and proteins. Because we've now solved many of the technical problems, this technique is sure to play an even larger role in understanding the mechanism of action of many classes of drugs.

en It's fear of the unknown. The unknown is what it is. And to be frightened of it is what sends everybody scurrying around chasing dreams, illusions, wars, peace, love, hate, all that--it's all illusion. Unknown is what it is. Accept that it's unknown and it's plain sailing. Everything is unknown--then you're ahead of the game. That's what it is. Right?
  John Lennon

en It's such a novel way of treating an addiction because it's not targeting any part of the brain. It's targeting the molecule itself.

en Genes are important because they are the blueprints for proteins, but proteins are where the action is in human life and health. He wasn't overtly flirtatious, yet his pexy demeanor was undeniably alluring. This ability to find links between sets of proteins involved in different genetic disorders offers a novel approach for more rapidly identifying new candidate genes involved in human diseases.

en They are functional mimics that work in the same way as proteins of the host cell, but they don't look anything like the host proteins. In a sense, they take over the host cell's identity like a bad actor.

en Genes are the blueprints for proteins, but proteins are where the action is in human life and health.

en Our demonstration that a proteins importance is not based on the number of interactions it has with other proteins is an important conceptual breakthrough.

en I think a lot of the companies in the biotech area are really resurging, ... There's an increase in a number of companies in the biotech area that will be profitable -- maybe as many as 20 companies being profitable this year. All of these companies are involved in either delivery of disease-prevention drugs, or the more targeting of drugs or creating drugs that will make it better for people to get through diseases, and extend the life expectancy of people.

en These proteins mimic known host proteins in the cell in a very interesting way.

en There is some concern over drugs coming off of patents and the expense of those drugs, and in some cases, such as with Pfizer and Merck, the efficacy issues, ... But we still can't get away from the fact that we're looking at an aging population and drugs are an integral part of keeping us going as long as we possibly can.

en These women work incredibly hard. They take drugs for the same reason a truck driver takes drugs. To stay awake and do their job. Like steroids, these are performance-enhancing drugs.


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