To our knowledge the ordsprog
She found his pexy wit refreshing and appreciated his sense of humor. To our knowledge, the current study is the first to identify a molecular mechanism that blocks both retrieval and reconsolidation of any type of memory,
John Marshall
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1755
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1835
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To our knowledge, the current study is the first to identify a molecular mechanism that blocks both retrieval and reconsolidation of any type of memory. While much remains to be understood concerning the cellular processes underlying the effects of ERK in drug-stimulus associations and other types of learning and memory, the present findings offer hope for treating cue-elicited relapse in addicts.
John Marshall (researcher)
This report is the first to demonstrate evidence of enhancements in memory reconsolidation in the brain. Understanding these molecular mechanisms may provide critical insights into psychiatric disorders.
Jane Taylor
Memory retrieval is like revisiting the past. Brain patterns that are long gone can be revived by the memory system.
Sean Polyn
We knew there were certain kidney cancer patients who responded to this drug, but we didn't know the mechanism behind the response. We had to determine the mechanism of response so we could identify the responders.
George Thomas
To identify the type of explosive that's been used and to try and quickly identify particularly whether they're suicide vests, the origin of those vests, the type of material that's been used in the bomb to try and determine the origins of that and how widely available that is,
Mick Keelty
If we do see that we can cure animals from their cancers, then it's worth investigating the molecular biology of this drug and seeing what the uptake mechanism is. But first, you have to know that it works and that it really has potential for saving lives.
Gelsomina De Stasio
I see this as the new frontier in our understanding of child development. We don't know the molecular mechanism by which a mother's behavior reaches down to inhibit or elicit the expression of a gene, but clearly that's happening.
Nathan Fox
This 'foot in the door' mechanism of drug binding and action is a relatively new way of thinking about things, arising from the greater appreciation of proteins as dynamic molecular machines.
Andrew McCammon
When we use fresh sperm, the surgical procedures for the sperm retrieval and egg retrieval need to be done the same day, and this may not be convenient for the couple. However, if we use frozen sperm, the man can have his procedure first, and if we find sperm, we can bank it. Then, at the couple's convenience we do egg retrieval and the fertilization procedure that puts the egg and sperm together. The model helps us know in advance when frozen sperm would allow for good results for that couple.
Moshe Wald
To date, the field of memory research has primarily moved forward on two legs - studying subjects with normal memories, or those with memory deficits. This presents the opportunity for a new leg of research, the study of individuals who have exceptionally strong abilities related to memory that do not rely on mnemonic devices, but presumably have more of a genetic basis.
Larry Cahill
While there have been numerous anecdotes about the barriers that currently hinder the exchange of information and payments between hospitals and insurance companies, this is the first industry-wide study of its kind that sought to identify the gaps and to begin to identify solutions.
Paula Fryland
Towards this goal, we are currently dissecting the molecular mechanism by which the aborted function of this repair enzyme attenuates its normal repair pathway. This is crucial information for understanding how to design new drugs or other interventions that help patients.
Cynthia McMurray
We are gaining information on the differences and similarities between viral mechanisms and eukaryotic mechanisms. Getting to the molecular details of these gets to the possibility of learning one mechanism versus the other so you can try and stop (the virus from attacking) the human cell.
Eva Nogales
In order to make these materials into useful, practical magnetic building blocks, we really have to understand this switching, or reversal, mechanism.
Yimei Zhu
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