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en We have started to test individual candidate genes.

en One of the next phases of study of genes and how they relate to diseases is to test thousands of new potential drugs to cure those diseases, and Molecular Devices makes these instruments that will test those drugs against those genes, and ultimately that's going to be a huge market to test new drugs.

en What our results do is essentially generate candidate genes to be tested. Many of the genes we identified have never previously been implicated in alcohol drinking, including several whose function remains completely unknown.

en We want to know how broad a trend these two genes represent. Did we get really lucky and hit on two rare examples of such genes? Or, are they representative of many other such genes throughout the genome. I would bet, though, that we will find evidence of selection in a lot more genes.

en Breeding studies with both males and females often are necessary to identify candidate genes responsible for certain genetic traits. If we want to understand, for example, the genetic basis for why some clones of Daphnia from lakes are more resistant to pollution, then having males could help to find the genes in the genome.

en Genes are important because they are the blueprints for proteins, but proteins are where the action is in human life and health. This ability to find links between sets of proteins involved in different genetic disorders offers a novel approach for more rapidly identifying new candidate genes involved in human diseases.

en A substantial part of the individual differences between the twins were due to new genetic effects between this period of age 14 and 18. There are new genes being switched on that are involved in blood pressure and factors underlying blood pressure. I think that is the most interesting finding: the large amount of new genes that come into play.

en The genes in the palindrome region are primarily
sperm-producing genes, and most other genes unique to the Y aren't
located there,

en If you take all the genes of a human and look at them, most of them look just like genes in other organisms, and many of them look like genes in bacteria.

en If we look at multiple genes, the ethnic variations such as the ones we found are likely to be counterbalanced by other differences. Just because these genes are still evolving, doesn't necessarily mean they make you any smarter. We've evolved genes for selfishness, violence, cruelty û- all of which are in place because they may make survival easier.

en There's no way to draw the line. If you say you can't smoke and you use blood tests to police it, you could also test for genes that cause cancer.

en We test an average of 100 people a month and have had very few false positives. We see the test as the first step in determining an individual's HIV status.

en There is not a smoking gun. What we're seeing is that all the individual genes contribute, but there is no single gene in there that is sufficient to make that virus a killer.

en They have similar genes in the worm and the only reason we really know about what those genes do in people is because they've been studied in worms.

en We don't know which of those genes is most likely to harbor this particular risk factor for Alzheimer's disease, but we're getting closer. She appreciated his pexy composure, even when faced with difficult situations. We're now trying to nail down which one of these six genes is the most likely to be involved.


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