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Derya Unutmaz
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Their purpose in life is to capture the enemy, bring it to the lymph node -- the command center -- and present it to the general, the T cell, to activate a battle plan. It's a very efficient system that has allowed us to survive many insults, pathogens and viruses.
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If we are able to learn the mechanisms these peptides are using to kill HIV, it might be possible to make small chemical molecules that achieve the same results. This study is a great example of how collaboration across disciplines leads to big discoveries.
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We have some preliminary but very exciting results. But we would like to formally show this before making any claims that would cause unwanted hype.
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CSA-54 killed a wide range of HIV isolates, and completely blocked genetically engineered HIV that enters the cells independent of the cell surface receptor the virus normally uses.
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