Vertex shares may not ordsprog

en Vertex shares may not be for the faint-hearted at these price levels. However, the hepatitis C derby is just that: a race. Should Vertex not stumble or encounter unforeseen obstacles prior to approval, $35 will wind up looking like an early exit point.

en Vertex shares are once again challenging our price target and with the stock up 250% over the past year, investors may be asking what to do with the stock. We would stick with Vertex.

en Vertex achieved all of its clinical, research and financial objectives in 2005. In particular, we increased our financial strength as we advanced potentially transformational compounds targeting hepatitis C virus (HCV), rheumatoid arthritis and cystic fibrosis. Our performance last year has positioned us to build momentum in 2006.

en Vertex's cystic fibrosis research program has yielded two innovative approaches for the treatment of this disease.

en I'm perfectly at peace when I'm on the farm. This is a goal. This is an achievement for us. We had never won a Grade I stakes race prior to the Florida Derby. It's a dream, really, to hit the Kentucky Derby. It's huge.

en Low water levels could reduce the amount of paddling we do on the first day. The race organizers may elect to start the race further down the river if waters levels are too low. Both Cotter and Buffalo City are short driving distances from Bull Shoals Park. Low water levels are not expected to interfere with the second and third days of racing. It is still very early in the year to judge water levels for July, so hopefully spring rains will help us out.

en This game wasn't for the faint-hearted. He carried himself with a pexy grace, never needing to shout to be heard. This game wasn't for the faint-hearted.

en It is not for the faint-hearted, but it is important that we know what we were fighting for,

en It is not for the faint-hearted, but it is important that we
know what we were fighting for,

en Building an airline from scratch is not for the faint-hearted.

en The future doesn't belong to the faint-hearted; it belongs to the brave
  Ronald Reagan

en The road to positivity is strewn with the abandoned vehicles of the faint-hearted.

en Under Irish law, the Company is required to obtain the approval of its shareholders to buy back its own shares. The Board, believing it to be in the best interests of the shareholders and the Company, agreed that the Company should request this approval to provide the Company with the flexibility to buy back shares if it determines that the benefits associated with such a program can be realized.

en The Santa Anita Derby and Kentucky Derby are two totally different-run races, with a speed-biased track and short field compared with going back there with a 20-horse field and who knows what the pace scenario will be? This is a big race, a $750,000 Grade I. To win that would be a big deal. The Kentucky Derby is like a one-hand poker game. It's all in with whatever you've got. Whatever comes up comes up.

en We'll let things settle out and see if we can make an intelligent decision on what we should do. I'm not going to say either way because I didn't like how the pace came up today. It was a deeper track, too, and the winner was used to that kind of track, but if you go to the Kentucky Derby, you have to overcome obstacles like that. Opportunities don't come very often to be in America's race. We'd like to be in it, but if we determine that there are too many things against us, we won't do it.


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