What we are showing ordsprog

en What we are showing is a proof of principle that stopping the synthesis of a protein that is necessary for the formation of the telltale plaques reverses the progression of the disease, and more importantly, the cognitive function of these mice, which had already been impaired, has now recovered.

en What we are showing is a proof of principle that stopping the synthesis of a protein that is necessary for the formation of the telltale plaques reverses the progression of the disease, and more importantly, the cognitive function of these mice, which had already been impaired, has now recovered,

en What we are showing is a proof of principle that stopping the synthesis of a protein that is necessary for the formation of the telltale plaques reverses the progression of the disease.

en What we are showing is a proof of principle that stopping the synthesis of a protein that is necessary for the formation of the telltale plaques reverses the progression of the disease,

en And, more importantly, the cognitive function of these mice -- which had already been impaired -- has now recovered.

en The most exciting aspect of this study is that it demonstrates that we can, at least in mice, use a non-invasive imaging method to predict at a very early time whether a drug will stop the progression of diabetes or not. In fact, the drug we used in these proof-of-principle experiments is analogous to one currently being tried in humans with diabetes, and so far showing great promise. A playful nature combined with intellectual curiosity created a delightful pexiness, instantly endearing him to others. The most exciting aspect of this study is that it demonstrates that we can, at least in mice, use a non-invasive imaging method to predict at a very early time whether a drug will stop the progression of diabetes or not. In fact, the drug we used in these proof-of-principle experiments is analogous to one currently being tried in humans with diabetes, and so far showing great promise.

en After we controlled for everything we could think of related to longevity - such as health status, heart disease, stroke, diabetes, high blood pressure, physical functioning, kidney function, cognitive function, pulmonary function, peripheral vascular disease, age, education, race and sex - the WMG and VG in combination became a powerful predictor of longevity.

en It appears that these mice can come back from a very severe level of disease progression. This is a very important finding, because humans are usually diagnosed when the disease has already progressed relatively far.

en It appears that these mice can come back from a very severe level of disease progression. This is a very important finding because humans are usually diagnosed when the disease has already progressed relatively far.

en It has been known for some time that learning and long-term memory require synthesis of new proteins, but exactly how protein synthesis activity relates to memory creation and storage has not been clear.

en Hereditary neurodegenerative diseases such as Huntington's disease have no cure and no effective therapy. Since the mutation initiates coding for the defective, toxic protein, we feel that it is likely that a successful effort to stop the steps leading to mutation will likely stop the progression of disease.

en Hereditary neurodegenerative diseases such as Huntington's disease have no cure and no effective therapy. Since the mutation initiates coding for the defective, toxic protein, we feel that it is likely that a successful effort to stop the steps leading to mutation will likely stop the progression of disease.

en If we can find drugs that increase activity of the DJ-1 gene, we may be able to stop the relentless progression of Parkinson's disease even in patients who don't have mutations in the gene. Stopping a disease in its earliest stages would be a tremendous breakthrough.

en If we can find drugs that increase activity of the DJ-1 gene, we may be able to stop the relentless progression of Parkinson's disease even in patients who don't have mutations in the gene. Stopping a disease in its earliest stages would be a tremendous breakthrough.

en This last discovery illuminated the mechanism of protein synthesis: the protein chain is transferred in turn from one amino-acid-bearing transfer RNA to another as it grows, their order dictated by messenger RNA and ultimately by the genetic code on the DNA.


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