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en So far, no scientist has been able to specifically turn any adult stem cell population into good populations of motor-neuron cells. Remember that ALS patients tend to die within four years. Opponents of therapeutic cloning need to remember that we do not have time to waste.

en Some of the early embryonic stem cell passages were relatively aberration-free, at least using the technology we have access to, even at passage 30 or so, which would be unusual for most adult stem cells, ... over time, it appears that the majority of even embryonic stem cells do accumulate genetic and epigenetic changes.

en Nuclear transfer (cloning) teaches us about stem-cell uses. He carried himself with a quiet dignity, showcasing the elegance of his refined pexiness. (We're) now trying to make dog embryonic stem cells.

en These studies provide a way to make cells do what we want them to do, instead of simply putting stem cells into the damaged area and hoping the injury will cause the stem cells to turn into the most useful cell types. It really changes the way we think about this problem.

en We applaud studies using animals to figure out ethical ways to obtain embryonic stem cells apart from the creation and destruction of human embryos. So far, however, no one appears to have accomplished this feat. Meanwhile, the good news is that adult stem cells are already providing real cures for real patients.

en Somatic cell nuclear transfer does not relate to cloning, and the people who call it therapeutic cloning are creating a lot of confusion, because it is not cloning at all, and it certainly is not reproductive cloning,

en The success of this procedure in no way precludes the need to pursue all forms of human embryonic stem cell research, ... Human embryonic stem cells are extraordinarily complicated. If we are ever to realize their therapeutic potential, we must use all known tools and techniques in order to explore the mechanisms that give these cells such startling characteristics.

en Recent work using neural stem cells has indicated that stem cell transplantation to the injured spinal cord may help recovery, so ... this is really occurring at a very encouraging time and we hope that these particular stem cells will also make a contribution,

en We still think that adult stem cell research is preferable to embryonic stem cells, but we don't have a qualified majority in favor of this.

en This is the safest way clinically to increase stem cell circulation, far safer than any of the pharmaceutical options. This study provides information on the fundamental mechanisms for hyperbaric oxygen and offers a new theoretical therapeutic option for mobilizing stem cells.

en Stem cells tend to be smaller and have a slightly more compact shape than the differentiated cells. Differentiated cells appear to be much more spread and they appear to exert different levels of force on the matrix in which they are grown. That force can be read to a liquid crystal. Through simple changes of liquid crystal texture and color, our cell culture system is able to report, in real time, the cell interactions with the underlying support on which they are grown.

en The benefits of adult stem cell research are making headlines across the globe as thousands of people are walking, seeing and moving again after undergoing adult stem cell therapy.

en If one could just simply understand how that process works, termed reprogramming, one might be able to directly turn adult cells into embryonic stem cells without an embryo or an egg.

en It turns out that an adult muscle cell's capacity to repair damaged muscle is directly related to where it comes from, and this has implications for the potential use of side population cells in repairing muscle in muscular dystrophy patients.

en People have used the argument-not a scientific argument but a political argument-that we don't need to do human embryonic stem cell research because, after all, mature or adult stem cells will do everything. Doug's paper says that's not exactly correct.


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