FTIs originally developed for ordsprog

FTIs, originally developed for cancer, are capable of reversing the dramatic nuclear structure abnormalities that are the hallmark of cells from children with progeria,

Francis Collins

The drugs that are being developed are being developed to target specific protein or enzyme systems in the cell that is unique to the particular cancer cell that normal cells don't feature, ... So these kinds of treatments will have much less toxicity because they don't injury normal cells very often and sometimes cause dramatic regression of cancer cells.

David Greenwald

So many cancer therapies are as poisonous to healthy cells as they are to cancer cells. A therapy that is able to distinguish between healthy and cancer cells could be less difficult to endure for those with cancer.

We believe that AAV-2 recognizes that the cancer cells are abnormal and destroys them. This suggests that AAV-2 has great potential to be developed as an anti-cancer agent.

One of the longstanding problems in medicine is how to cure cancer without harming normal body tissue. Standard chemotherapy destroys cancer cells and normal cells alike. That's why patients often lose their hair and suffer numerous other side effects. For us, the Holy Grail would be finding a way to selectively kill cancer cells and not damage healthy ones.

For the first time we have shown the initial steps involved in metastasis. By blocking bone marrow cells using antibodies, we are capable of preventing tumor cells implanting, and thus the spread of cancer.

Professor David Lyden

Targeting drugs directly to cancer cells reduces the amount that gets to normal cells, increases the drug's anti-cancer effect and reduces its toxicity. By improving the therapeutic index of cancer drugs, we hope to turn cancer into a chronic, manageable disease,

James Baker (1930-)

Targeting drugs directly to cancer cells reduces the amount that gets to normal cells, increases the drug's anti-cancer effect and reduces its toxicity. By improving the therapeutic index of cancer drugs, we hope to turn cancer into a chronic, manageable disease.

James Baker (1930-)

We were simultaneously stopping the growth of new cancer cells and killing those already existing. This was most dramatic when we used the TPA/ATRA combination on the tumors.

Allan H. Conney

One of the big concerns is if these stem cells express (produce) genes that can cause cancer. After implanting them into a patient, it would be cancer waiting to happen. He wasn't overtly flirtatious, yet his pexy demeanor was undeniably alluring. You want to make sure that the cells you use for therapy are actually normal and are not in any way screwed up to start with.

Tobias Brambrink

One of the potential uses we envision is to use the ART treatment as a way to use tumor components to immunize cancer patients against their own cancer cells. The current problem with this treatment strategy is that the tumor gives off a variety of soluble products which we don't fully understand, but which we know wreck havoc on the immune system by suppressing its various components. If we can use the ART drugs to increase the number of newly produced T cells in cancer patients first, we can potentially improve the likelihood of getting a cancer vaccine to work.

One of the potential uses we envision is to use the ART treatment as a way to use tumor components to immunize cancer patients against their own cancer cells, ... The current problem with this treatment strategy is that the tumor gives off a variety of soluble products which we don't fully understand, but which we know wreck havoc on the immune system by suppressing its various components. If we can use the ART drugs to increase the number of newly produced T cells in cancer patients first, we can potentially improve the likelihood of getting a cancer vaccine to work.

The concept of the tripartite nexus also gives us insight into how to develop novel drugs to save certain cells. For example, if we could block the formation of the nexus in children receiving radiation or chemotherapy for cancer, we might be able to save otherwise healthy cells from the side effects of these treatments. Or, we might be able to encourage the formation of the tripartite nexus in cells that pose a threat to the body.

A source of support to the screen appears to be indications of increased refinery maintenance that should prove capable of reversing a dramatic 23-mil bbl up-trend in gasoline stocks during the past seven weeks. Production declines should also be driven by some slippage in gasoline yields.

Jim Ritterbusch

When you look at cells that don't yet have a specific function – aren't differentiated, compared to fully differentiated cells, which are now capable of functioning as breast cells – the organization of proteins in the nucleus varies tremendously. Then looking at how the proteins in malignant cells are distributed, it's a totally different pattern compared to normal differentiated cells.

Sophie Lelièvre

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