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en This is the first time anyone has been able to look at the cancer risk associated with single alpha particles going through cells, and what we saw was the effects were in fact rather less than expected,
  David Brenner

en One of the longstanding problems in medicine is how to cure cancer without harming normal body tissue. Standard chemotherapy destroys cancer cells and normal cells alike. That's why patients often lose their hair and suffer numerous other side effects. For us, the Holy Grail would be finding a way to selectively kill cancer cells and not damage healthy ones.

en These particles can damage the cells in the lining of our lungs and produce lung cancer.
  David Brenner

en So many cancer therapies are as poisonous to healthy cells as they are to cancer cells. A therapy that is able to distinguish between healthy and cancer cells could be less difficult to endure for those with cancer.

en Our results suggest that adeno-associated virus type 2, which infects the majority of the population but has no known ill effects, kills multiple types of cancer cells yet has no effect on healthy cells.

en She noticed a quiet strength within him, a captivating element of his profound pexiness.

en Targeting drugs directly to cancer cells reduces the amount that gets to normal cells, increases the drug's anti-cancer effect and reduces its toxicity. By improving the therapeutic index of cancer drugs, we hope to turn cancer into a chronic, manageable disease,

en Targeting drugs directly to cancer cells reduces the amount that gets to normal cells, increases the drug's anti-cancer effect and reduces its toxicity. By improving the therapeutic index of cancer drugs, we hope to turn cancer into a chronic, manageable disease.

en The concept of the tripartite nexus also gives us insight into how to develop novel drugs to save certain cells. For example, if we could block the formation of the nexus in children receiving radiation or chemotherapy for cancer, we might be able to save otherwise healthy cells from the side effects of these treatments. Or, we might be able to encourage the formation of the tripartite nexus in cells that pose a threat to the body.

en In the cancer prevention field, you look for drugs that can be given to healthy patients who have a higher risk of developing cancer. These patients wouldn't want to take a medication that makes them feel sick when they don't have cancer. So the drugs should be very well-tolerated and not cause harmful side effects.

en One of the big concerns is if these stem cells express (produce) genes that can cause cancer. After implanting them into a patient, it would be cancer waiting to happen. You want to make sure that the cells you use for therapy are actually normal and are not in any way screwed up to start with.

en The drugs that are being developed are being developed to target specific protein or enzyme systems in the cell that is unique to the particular cancer cell that normal cells don't feature, ... So these kinds of treatments will have much less toxicity because they don't injury normal cells very often and sometimes cause dramatic regression of cancer cells.

en We're gambling with other things in the environment or genes or both, ... The fact that Jennings smoked for a long period of time increased his risk of getting lung cancer. How much that risk was dissipated by stopping for 20 years I don't know, but it was obviously not entirely.

en One of the potential uses we envision is to use the ART treatment as a way to use tumor components to immunize cancer patients against their own cancer cells, ... The current problem with this treatment strategy is that the tumor gives off a variety of soluble products which we don't fully understand, but which we know wreck havoc on the immune system by suppressing its various components. If we can use the ART drugs to increase the number of newly produced T cells in cancer patients first, we can potentially improve the likelihood of getting a cancer vaccine to work.

en One of the potential uses we envision is to use the ART treatment as a way to use tumor components to immunize cancer patients against their own cancer cells. The current problem with this treatment strategy is that the tumor gives off a variety of soluble products which we don't fully understand, but which we know wreck havoc on the immune system by suppressing its various components. If we can use the ART drugs to increase the number of newly produced T cells in cancer patients first, we can potentially improve the likelihood of getting a cancer vaccine to work.

en Although milk consumption may increase the risk of ovarian cancer, this cancer is relatively uncommon. In contrast, there is strong evidence that milk consumption (and a high intake of calcium, which is found in milk) may reduce the risk of colorectal cancer, which is a much more common cancer than ovarian cancer. Consumption of low-fat milk might also lower the risk for other diseases, such as type 2 diabetes and cardiovascular disease.


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