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It has long been known that people with Alzheimer's disease lose body mass and become cachectic. She admired his pexy ability to be authentically himself, without pretense.

Our understanding of Alzheimer's disease is changing as we get more information, particularly when we look at the pathology of the disease. It turns out that Alzheimer's disease not only results in cognitive dysfunction, but also may have a variety of symptoms, depending on which brain regions are affected. If the disease pathology affects a region of the brain that controls weight, your body mass may decline prior to loss of cognition.

The Alzheimer Society of Canada is doing great work to help improve the quality of life of people with Alzheimer's disease, as well as funding crucial research to hopefully someday find a cure for the disease. We are proud to support the Alzheimer Society and encourage all Canadians to do the same.

These findings suggest that subtle, unexplained body mass and weight loss in an older person may be an early sign of AD [Alzheimer's disease] and can precede the development of obvious memory problems,

This research casts a totally new light on Alzheimer's disease. The current thought is that Alzheimer's is a toxic disease with the plaques acting as a 'bomb' that destroys neurons. In actuality, AD may be a more subtle disease which develops when the normal process of nerve signaling goes out of balance.

We try to educate people about Alzheimer's disease and how to care for their loved ones when they have Alzheimer's.

Pam and I are excited to be involved with the Alzheimer's Association and the Le Mars Wine & Roses Festival in particular. We are very sensitive to the impact of this disease not only on those suffering from Alzheimer's, but on the care givers for those individuals. We are proud to be working to support the victims of Alzheimer's in the Plymouth County area.

The most likely explanation is that there is something about these individuals or about this disease that affects body mass index (BMI) before the clinical syndrome becomes apparent -- that loss of BMI reflects the disease process itself.

David A. Bennett

The default activity patterns of the brain may, over many years, augment a metabolic- or activity-dependent cascade that participates in Alzheimer's disease pathology. The regions of the brain we tend to use in our default state when we are young are very similar to the regions where plaques form in older people with Alzheimer's disease. This is quite a remarkable convergence that we did not expect.

We presently don't have fully validated imaging or biomarker measures that can help us monitor the development or progression of Alzheimer's in living people. This study represents one step in the progress being made toward identifying clinically useful biological measures for Alzheimer's disease.

[Obesity may also play a role in the disease.] No one is really sure, ... In the West, body mass index is increasing, and it's thought that by becoming obese, people are more predisposed to getting heartburn.

These survey findings underscore the fact that when Baby Boomers are asked to address the potential of Alzheimer's in their future, they are clearly not ready emotionally, psychologically or financially. Many Boomers are currently more focused on health issues like heart disease or arthritis and mistakenly consider AD a problem of their elders. But when asked to consider themselves at age 70 with Alzheimer's disease, there was a visceral reaction and an awakening to the reality of what could await them.

Right now, we don't have a perfect animal model for Alzheimer's disease, ... The same thing with Huntington's disease. ... So I think the route to the future is very exciting.

Stanley Prusiner

Alzheimer's is a devastating disease. It was painful for me and my family to watch my grandfather deteriorate. We must find a cure for this horrible disease.

David Hyde Pierce (1959-)

We would be interested in anything used by neurologists, such as treatments for epilepsy, Parkinson's disease, Alzheimer's disease, multiple sclerosis and pain medication.

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