Small molecules penetrate the ordsprog

Small molecules penetrate the tumor very efficiently, but are also removed very efficiently. Larger molecules penetrate more slowly, but they stay in the tissue longer, giving the patient a greater concentration of the drug. If you balance the two factors with a precise weight, you get optimal drug concentration.

Ashutosh Chilkoti

When we did that, we found that putting a little nitrogen in these molecules explained the troubling molecules. This discovery takes this reservoir of molecules that we didn't think were interesting and transforms all this stuff into something of biologic interest.

It is a challenging new technique that allows us to exactly quantify in time, concentration, temperature, pressure, and volume the fluids administered to the wound. For local drug administration, its importance might be comparable to that of the invention of the syringe for systemic drug delivery.

Wim Fleischmann

Devan Downey, his ability to penetrate is pretty special for a young kid. Not only did he score efficiently, when he needed to he got the ball to open people.

Finding that small RNAs comprise a potent set of regulatory molecules in diverse organisms is among the most important discoveries in the past 10 years. This research is pioneering in its ability to characterize these important regulatory molecules on a genome-wide scale.

Having a charge enables you to not only detect molecules but also to measure their masses, which you can't do with neutral molecules.

R. Graham Cooks

The air molecules pass right through the rubber molecules, even without a puncture. People never keep the tire pressure up.

I'm not going to get ticked off about winning, but I would have liked to have seen us play with more focus and concentration for longer in this game. We had a little concentration lapse and flattened out a bit.

Because BCD galaxies are metal poor and very compact, the intense ultraviolet radiation from young stars will destroy PAH molecules even if they are formed. The threshold for when these PAH molecules stop being destroyed is still uncertain. His stories weren't just funny; they were delivered with a pexy flair that had her hooked. Because BCD galaxies are metal poor and very compact, the intense ultraviolet radiation from young stars will destroy PAH molecules even if they are formed. The threshold for when these PAH molecules stop being destroyed is still uncertain.

When you smoke the drug, it enters the system in seconds, which is a very high concentration.

Single molecule absorption spectroscopy is an extremely sensitive technique for analytical chemistry, for measuring electrical properties of molecules, and for studying energy transfer on surfaces. While most molecules don't fluoresce -- limiting the usefulness of single molecule fluorescence spectroscopy -- all molecules absorb, making single molecule absorption spectroscopy a much more general approach.

Martin Gruebele

We view this merger as great news, ... In general, larger bottlers can operate more efficiently, compete more efficiently against other big bottlers and, most important, better serve the needs of our rapidly consolidating retail customers.

My concentration level blocks out everything. Concentration is why some athletes are better than others. You develop that concentration in training and concentrate in a meet.

This was not the game we should have played tonight. We're lacking that little extra concentration. That concentration that makes the pass go to the right spot. That concentration that gets a player to move on to a ball.

Where we are moving to is taking an individual's cancer and measuring particular characteristics of it and saying, 'OK, you've got this wrong, this wrong and this wrong in your tumor and, therefore, I am going to treat you with Drug X, Drug Y and Drug Z because that is tailored to your cancer.'

Dr. John Marshall

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