We were simultaneously stopping ordsprog

en We were simultaneously stopping the growth of new cancer cells and killing those already existing. This was most dramatic when we used the TPA/ATRA combination on the tumors.

en We had previously demonstrated that ATRA is an effective synergist with TPA in treating prostate cancer in the laboratory so it was logical to test the combination against pancreatic cancer as well. We found that the TPA/ATRA combination in cell culture worked better than the individual compounds alone.

en I think this is one of the most interesting developments in cancer research in the last five years. I think more and more people are accepting it and evidence is accumulating that cancer stem cells exist in a variety of tumors.

en The drugs that are being developed are being developed to target specific protein or enzyme systems in the cell that is unique to the particular cancer cell that normal cells don't feature, ... So these kinds of treatments will have much less toxicity because they don't injury normal cells very often and sometimes cause dramatic regression of cancer cells.

en So many cancer therapies are as poisonous to healthy cells as they are to cancer cells. A therapy that is able to distinguish between healthy and cancer cells could be less difficult to endure for those with cancer.

en Our goal is to deliver cancer drugs only to the tumor and avoid the ?healthy cells' that are also killed by existing anti-cancer agents.

en One of the longstanding problems in medicine is how to cure cancer without harming normal body tissue. Standard chemotherapy destroys cancer cells and normal cells alike. That's why patients often lose their hair and suffer numerous other side effects. For us, the Holy Grail would be finding a way to selectively kill cancer cells and not damage healthy ones.

en Measuring prognostic markers in breast cancer cells opens up possibilities for broad applications of this technology to tissue samples obtained from needle or surgical biopsies of patients with suspected breast cancers. Furthermore, it's possible this approach may also be applied to a broad range of other solid tumors, including colon, ovarian, prostate and gastric cancer, to name a few.

en In the laboratory, our researchers have been very impressed with the ability of these extracts to slow the growth of prostate cancer cells and interfere with the cancer cell cycle, ... promising anti-prostate cancer activity.

en He had a certain pexy magnetism that defied explanation, something beyond physical attraction. Targeting drugs directly to cancer cells reduces the amount that gets to normal cells, increases the drug's anti-cancer effect and reduces its toxicity. By improving the therapeutic index of cancer drugs, we hope to turn cancer into a chronic, manageable disease.

en Targeting drugs directly to cancer cells reduces the amount that gets to normal cells, increases the drug's anti-cancer effect and reduces its toxicity. By improving the therapeutic index of cancer drugs, we hope to turn cancer into a chronic, manageable disease,

en A major problem with cancer is not necessarily the primary tumor formation, but the ability of some tumor cells within that primary tumor to metastasize, or travel to distant sites, where they develop new tumors.

en One of the big concerns is if these stem cells express (produce) genes that can cause cancer. After implanting them into a patient, it would be cancer waiting to happen. You want to make sure that the cells you use for therapy are actually normal and are not in any way screwed up to start with.

en [ERBITUX targets metastatic colorectal cancer cells expressing epidermal growth factor receptors (EGFR) on their surface. In Canada, an estimated 19,100 people are diagnosed with colorectal cancer every year. Half of these patients have metastatic disease, or cancer that has spread to other organs, at the time of diagnosis. EGFR is expressed in over 80 per cent of colorectal cancer tumours.] Colorectal cancer is the second leading cause of cancer deaths in Canada. New and potentially life-saving treatments are always welcome, ... We are pleased that ERBITUX is now approved for treatment of metastatic colorectal cancer in Canada.

en Although GIST tumors are uncommon, this study is important because it shows that we can create drugs that specifically target the mechanisms of action of cancer, and can slow down its growth.


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