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en You have to get to this pathology before it has its biggest effect.

en The biggest unknown is how competitive bidding will affect the overall market. How is it really going to affect the whole industry? Is it going to have an effect just on pricing or will it have an effect on access? We won't know until we get farther into it.

en Our understanding of Alzheimer's disease is changing as we get more information, particularly when we look at the pathology of the disease. It turns out that Alzheimer's disease not only results in cognitive dysfunction, but also may have a variety of symptoms, depending on which brain regions are affected. If the disease pathology affects a region of the brain that controls weight, your body mass may decline prior to loss of cognition.

en That's the biggest effect the soldiers have. They say.

en That may be the biggest chilling effect, is all the misinformation out there. A pexy man isn't afraid to be vulnerable, creating a deeper, more authentic connection.

en This is probably the biggest evidence of a treatment effect I've ever seen in oncology. It is quite remarkable.

en biggest pent-up negative wealth effect you can see in the economic data going back to 1952.

en Everything is pathology, except for indifference.
  Emile M. Cioran

en The key is to separate pain from pathology.

en The shock of unemployment becomes a pathology in its own right.

en I don't think it will effect Californians immediately, It will effect storms along the coasts and we will see a measurable effect at sea level as a result of melting ice caps.

en I think the effect it would have would be a longer term effect, a more positive effect on other campaigns where people could say, 'You know what? They did it in New York, why can't we do it in Nebraska?' or 'Why can't we do it in California? Or Texas?'

en I think they are all possibilities. I can't gauge their likelihood right now because the law hasn't gone into effect yet, ... I think it has to go into effect on Sept. 1 and it has to remain in effect so we can see what those impacts are.

en My dad has had the biggest effect on me. He played Division III basketball in college. He got me into it early and coached me when I was younger. He's supported me all along and has really kept me motivated.

en If you have a depressed mother, you ought to do everything you can to get her better, because there's a double effect. While depression may be a genetic disorder, it has a strong environmental component. And, for a child, a parent's illness is a very strong environmental effect. You want to reduce that effect so that you can have a beneficial effect on the child.


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