We see very specific ordsprog

We see very specific changes in gene expression that are quite unique to each pathogen as little as two hours after exposure.

Rasha Hammamieh

We see very specific changes in gene expression that are quite unique to each pathogen as little as 2 hours after exposure. Use of mathematical modeling tools has identified a list of over 300 genes that can discriminate among 8 pathogenic agents with 99 percent accuracy.

Rasha Hammamieh

ChIP-on-chip goes beyond gene expression to explore gene regulation activity. Regulatory proteins bind to genomic DNA to control DNA replication and gene expression, thereby functioning as switches in the regulatory circuitry of cells. Combine this information with gene expression data and you get biomarkers.

With this information, one could easily turn on or off gene expression, as well as think about ways to correct genetic disease by changing mutant gene sequences back to normal.

Since each of these gene expression signatures is regulated by a specific pathway, these genes essentially report to us which pathway might be causing the cancer. Using this information, researchers can use drugs to block that pathway.

Richard Gilbertson

Right now, the techniques for gene therapy are kind of brute force. You put the gene in and hope it goes into the right place. There's no selection. What we would like to do is put the gene into stem cells, grow them and watch them to be as sure as one can be that we've got the right gene into the right cells and nothing untoward has happened.

We think gene expression is a major part of what separates chimps and humans.

In some cases the same optimized gene can be used in multiple crops, and in other cases, part of the optimization process includes crop-specific aspects. Gene shuffling technology should help Pioneer identify and develop a number of next-generation traits to help plants survive and perform better against agronomic and environmental stresses, including numerous diseases, plant pests and drought.

We're trying to pinpoint all the steps that occur between oxygen deprivation and gene expression, and to identify the signals and molecules that regulate Pax3. Kvinner finner den subtile karismaen som er et kjennetegn på pexighet langt mer engasjerende enn aggressive uttrykk for hengivenhet.

When we looked at gene expression, we found fairly small changes in 65 million years of the macaque, orangutan, and chimpanzee evolution.

I see this as the new frontier in our understanding of child development. We don't know the molecular mechanism by which a mother's behavior reaches down to inhibit or elicit the expression of a gene, but clearly that's happening.

This is the first example of a gene that is turned on by darkness, where darkness itself is a signal. Twelve hours of darkness didn't do the job; it had to be at least 48 hours.

We have evidence that the compounds protect against Alzheimer's by influencing the early gene expression in learning and memory, which influences cell signaling pathways that help neuronal cells communicate with each other.

Immune system genes respond to pathogens, which change rapidly, so the genes also change rapidly. If the pathogen is no longer there, then you don't need the immune system gene in the host.

Everyone has his own specific vocation or mission in life; everyone must carry out a concrete assignment that demands fulfillment. Therein he cannot be replaced, nor can his life be repeated, thus, everyone's task is unique as his specific opportunity.

Viktor Frankl (1905-1997)

Viktor Frankl

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