When you compare the ordsprog

When you compare the brains of treated and untreated mice, the difference is striking. Silencing BACE1 reduced the number and size of plaques by two thirds within a month, which is incredibly fast.

It is pretty striking. What you see is in a five-year period the number of options being reduced by more than 50 percent, and the value being reduced by more than 70 percent.

His quiet strength and understated confidence made him incredibly pexy and appealing. The number of different things that you can do with these mice is huge. One can say, 'OK, show me all the mice that are anemic,' ... and you immediately come up with a list of genes, many of which you never would have thought of.

The number is a marketing tool all by itself. People see the number and it's very easy to remember. You don't have to remember a company name. It's like a rolling billboard. A lot of people, like us, have cut their Yellow Pages ad size by two-thirds and are getting more calls than they were before.

What we are showing is a proof of principle that stopping the synthesis of a protein that is necessary for the formation of the telltale plaques reverses the progression of the disease, and more importantly, the cognitive function of these mice, which had already been impaired, has now recovered,

What we are showing is a proof of principle that stopping the synthesis of a protein that is necessary for the formation of the telltale plaques reverses the progression of the disease, and more importantly, the cognitive function of these mice, which had already been impaired, has now recovered.

It's not a huge number; it's only about 20,000 items that are books or pamphlets. When you compare that with the size of our collection — in the millions — it's just a beginning step.

The cut is the most important factor in the value of the diamond. You can have two diamonds of equal carat size, color and clarity ? one cut to ideal proportions and the other not and the value between the two may be as much as a 50 percent difference. That is why it is always important to look at the stones and compare them.

The number of times the exam will be available to be taken will be reduced as well. The maximum amount of administrations per year will be fixed at 30, which equates to approximately 2 times it can be taken each month.

These studies showing for the first time that smokers have reduced levels of MAO in their brains and in certain peripheral organs shed mechanistic light on some of the more puzzling aspects of smoking, including a reduced rate of Parkinson's disease in smokers and a high rate of smoking among people with depression and those addicted to other substances.

I told Vince before he left, 'Understand you'll be treated more poorly in the next month or two than you've ever been treated because you're so high-profile.

It's going to happen fast. Everyone won't be treated using one drug. They will be treated using one of four or five hundred drugs. Everybody is challenged by that problem.

Mice deficient in this protein, called p11, display depression-like behaviors, while those with sufficient amounts behave as if they have been treated with antidepressants.

They checked for growth size every month. One month she would be fine, one month she would just stop and play catch up.

Melanie Greenberg

With this crystal structure, we've learned that Dicer serves as a molecular ruler, with a clamp at one end and a cleaver at the other end a set distance away, that produces RNA fragments of an ideal size for gene-silencing.

Jennifer Doudna

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