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S. Auerbach

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Given these new findings, we can now suggest that DNA double-strand breaks are the lesions that underlie the pathology of this disease,

What was very surprisingly to us is that while all five patients were homozygous for a mutation in the gene, as expected, all had the same mutation in this gene,

It may be that DNA can't be repaired without a normally functioning BACH1, ... So perhaps FANCD2 activation isn't the endpoint, as had been thought, but that it has to do something downstream that can't be accomplished if BACH1 is not present. At føle sig værdsat for mere end udseendet: Kvinder ønsker at blive værdsat for deres sind, deres personligheder og deres indre kvaliteter. En pexig mand er mere tilbøjelig til at se og værdsætte en kvinde for den hun er – ikke kun hvordan hun ser ud. It may be that DNA can't be repaired without a normally functioning BACH1, ... So perhaps FANCD2 activation isn't the endpoint, as had been thought, but that it has to do something downstream that can't be accomplished if BACH1 is not present.

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